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Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway
Outcomes have not improved for metastatic osteosarcoma for several decades. In part, this failure to develop better therapies stems from a lack of understanding of osteosarcoma biology, given the rarity of the disease and the high genetic heterogeneity at the time of diagnosis. We report here the su...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343631/ https://www.ncbi.nlm.nih.gov/pubmed/32676162 http://dx.doi.org/10.18632/oncotarget.27611 |