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Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway

Outcomes have not improved for metastatic osteosarcoma for several decades. In part, this failure to develop better therapies stems from a lack of understanding of osteosarcoma biology, given the rarity of the disease and the high genetic heterogeneity at the time of diagnosis. We report here the su...

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Detalles Bibliográficos
Autores principales: VanCleave, Ashley, Palmer, Mykayla, Fang, Fang, Torres, Haydee, Rodezno, Tania, Li, Qilin, Fuglsby, Kirby, Evans, Claire, Afeworki, Yohannes, Ross, Alan, Rao, Pulivarthi, Leiferman, Patricia, Zheng, Siyuan, Houghton, Peter, Tao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343631/
https://www.ncbi.nlm.nih.gov/pubmed/32676162
http://dx.doi.org/10.18632/oncotarget.27611