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(2S, 4R)-4-[(18)F]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models

PURPOSE: The glutamine analogue (2S, 4R)-4-[(18)F]fluoroglutamine ([(18)F]FGln) was investigated to further characterize its pharmacokinetics and acquire in vivo positron emission tomography (PET) images of separate orthotopic and subcutaneous glioma xenografts in mice. PROCEDURES: [(18)F]FGln was s...

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Detalles Bibliográficos
Autores principales: Miner, Maxwell WG, Liljenbäck, Heidi, Virta, Jenni, Merisaari, Joni, Oikonen, Vesa, Westermarck, Jukka, Li, Xiang-Guo, Roivainen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343746/
https://www.ncbi.nlm.nih.gov/pubmed/31993927
http://dx.doi.org/10.1007/s11307-020-01472-1