Preclinical Evaluation and Dosimetry of [(111)In]CHX-DTPA-scFv78-Fc Targeting Endosialin/Tumor Endothelial Marker 1 (TEM1)

PURPOSE: Endosialin/tumor endothelial marker-1 (TEM1) is an attractive theranostic target expressed by the microenvironment of a wide range of tumors, as well as by sarcoma and neuroblastoma cells. We report on the radiolabeling and preclinical evaluation of the scFv78-Fc, a fully human TEM1-targeti...

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Detalles Bibliográficos
Autores principales: Cicone, Francesco, Denoël, Thibaut, Gnesin, Silvano, Riggi, Nicolo, Irving, Melita, Jakka, Gopinadh, Schaefer, Niklaus, Viertl, David, Coukos, George, Prior, John O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343747/
https://www.ncbi.nlm.nih.gov/pubmed/31993928
http://dx.doi.org/10.1007/s11307-020-01479-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343747/
https://www.ncbi.nlm.nih.gov/pubmed/31993928
http://dx.doi.org/10.1007/s11307-020-01479-8

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