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The development of the dog heartworm is highly sensitive to sterols which activate the orthologue of the nuclear receptor DAF-12
Prevention therapy against Dirofilaria immitis in companion animals is currently threatened by the emergence of isolates resistant to macrocyclic lactone anthelmintics. Understanding the control over developmental processes in D. immitis is important for elucidating new approaches to heartworm contr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343802/ https://www.ncbi.nlm.nih.gov/pubmed/32641726 http://dx.doi.org/10.1038/s41598-020-67466-9 |