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The development of the dog heartworm is highly sensitive to sterols which activate the orthologue of the nuclear receptor DAF-12

Prevention therapy against Dirofilaria immitis in companion animals is currently threatened by the emergence of isolates resistant to macrocyclic lactone anthelmintics. Understanding the control over developmental processes in D. immitis is important for elucidating new approaches to heartworm contr...

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Detalles Bibliográficos
Autores principales: Long, Thavy, Alberich, Mélanie, André, François, Menez, Cécile, Prichard, Roger K., Lespine, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343802/
https://www.ncbi.nlm.nih.gov/pubmed/32641726
http://dx.doi.org/10.1038/s41598-020-67466-9