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AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study

Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, destruction, or functional blocking with impaired signal at the neuromuscular...

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Detalles Bibliográficos
Autores principales: Hong, Yu, Liang, Xiao, Gilhus, Nils Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343820/
https://www.ncbi.nlm.nih.gov/pubmed/32641696
http://dx.doi.org/10.1038/s41598-020-68185-x