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AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study
Acetylcholine receptor (AChR) antibodies are the most important pathogenic marker in patients with myasthenia gravis (MG). The antibodies bind to AChRs on the postsynaptic membrane, and this leads to receptor degradation, destruction, or functional blocking with impaired signal at the neuromuscular...
Autores principales: | Hong, Yu, Liang, Xiao, Gilhus, Nils Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343820/ https://www.ncbi.nlm.nih.gov/pubmed/32641696 http://dx.doi.org/10.1038/s41598-020-68185-x |
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