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Regulation of sister chromatid cohesion by nuclear PD-L1

Programmed death ligand-1 (PD-L1 or B7-H1) is well known for its role in immune checkpoint regulation, but its function inside the tumor cells has rarely been explored. Here we report that nuclear PD-L1 is important for cancer cell sister chromatid cohesion. We found that depletion of PD-L1 suppress...

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Detalles Bibliográficos
Autores principales: Yu, Jia, Qin, Bo, Moyer, Ann M., Nowsheen, Somaira, Tu, Xinyi, Dong, Haidong, Boughey, Judy C., Goetz, Matthew P., Weinshilboum, Richard, Lou, Zhenkun, Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343880/
https://www.ncbi.nlm.nih.gov/pubmed/32350394
http://dx.doi.org/10.1038/s41422-020-0315-8