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Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia
Autologous T cells engineered to express a chimeric antigen receptor (CAR) against the CD19 antigen are in the frontline of contemporary hemato-oncology therapies, leading to high remission rates in B-cell malignancies. Although effective, major obstacles involve the complex and costly individualize...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343910/ https://www.ncbi.nlm.nih.gov/pubmed/32714329 http://dx.doi.org/10.3389/fimmu.2020.01347 |