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Caspase-3 Activation Correlates With the Initial Mitochondrial Membrane Depolarization in Neonatal Cerebellar Granule Neurons

In this study we evaluated the effect of the reduction in the endoplasmic reticulum calcium concentration ([Ca(2+)](ER)), changes in the cytoplasmic calcium concentration ([Ca(2+)](i)), alteration of the mitochondrial membrane potential, and the ER stress in the activation of caspase-3 in neonatal c...

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Detalles Bibliográficos
Autores principales: Benítez-Rangel, Edaena, Olguín-Albuerne, Mauricio, López-Méndez, María Cristina, Domínguez-Macouzet, Guadalupe, Guerrero-Hernández, Agustín, Morán, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343937/
https://www.ncbi.nlm.nih.gov/pubmed/32714930
http://dx.doi.org/10.3389/fcell.2020.00544