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Congruence of Transcription Programs in Adult Stem Cell-Derived Jejunum Organoids and Original Tissue During Long-Term Culture

The emergence of intestinal organoids, as a stem cell-based self-renewable model system, has led to many studies on intestinal development and cell-cell signaling. However, potential issues regarding the phenotypic stability and reproducibility of the methodology during culture still needs to be add...

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Detalles Bibliográficos
Autores principales: van der Hee, Bart, Madsen, Ole, Vervoort, Jacques, Smidt, Hauke, Wells, Jerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343960/
https://www.ncbi.nlm.nih.gov/pubmed/32714922
http://dx.doi.org/10.3389/fcell.2020.00375