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Improved Prediction of Bacterial Genotype-Phenotype Associations Using Interpretable Pangenome-Spanning Regressions

Discovery of genetic variants underlying bacterial phenotypes and the prediction of phenotypes such as antibiotic resistance are fundamental tasks in bacterial genomics. Genome-wide association study (GWAS) methods have been applied to study these relations, but the plastic nature of bacterial genom...

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Detalles Bibliográficos
Autores principales: Lees, John A., Mai, T. Tien, Galardini, Marco, Wheeler, Nicole E., Horsfield, Samuel T., Parkhill, Julian, Corander, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343994/
https://www.ncbi.nlm.nih.gov/pubmed/32636251
http://dx.doi.org/10.1128/mBio.01344-20