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Improved Prediction of Bacterial Genotype-Phenotype Associations Using Interpretable Pangenome-Spanning Regressions
Discovery of genetic variants underlying bacterial phenotypes and the prediction of phenotypes such as antibiotic resistance are fundamental tasks in bacterial genomics. Genome-wide association study (GWAS) methods have been applied to study these relations, but the plastic nature of bacterial genom...
Autores principales: | Lees, John A., Mai, T. Tien, Galardini, Marco, Wheeler, Nicole E., Horsfield, Samuel T., Parkhill, Julian, Corander, Jukka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343994/ https://www.ncbi.nlm.nih.gov/pubmed/32636251 http://dx.doi.org/10.1128/mBio.01344-20 |
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