Functions and Clinical Significance of Super-Enhancers in Bone-Related Diseases

Super-enhancers (SEs) are a large cluster of cis-regulatory DNA elements that contain many binding motifs, which master transcription factors and cofactors bind to with high density. SEs usually regulate the expression of genes that can control the cell identity and fate, and SEs can be used to expl...

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Detalles Bibliográficos
Autores principales: Qu, Jian, Ouyang, Zhanbo, Wu, Wenqiang, Li, Guohua, Wang, Jiaojiao, Lu, Qiong, Li, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344144/
https://www.ncbi.nlm.nih.gov/pubmed/32714929
http://dx.doi.org/10.3389/fcell.2020.00534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344144/
https://www.ncbi.nlm.nih.gov/pubmed/32714929
http://dx.doi.org/10.3389/fcell.2020.00534

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