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Functions and Clinical Significance of Super-Enhancers in Bone-Related Diseases
Super-enhancers (SEs) are a large cluster of cis-regulatory DNA elements that contain many binding motifs, which master transcription factors and cofactors bind to with high density. SEs usually regulate the expression of genes that can control the cell identity and fate, and SEs can be used to expl...
Autores principales: | Qu, Jian, Ouyang, Zhanbo, Wu, Wenqiang, Li, Guohua, Wang, Jiaojiao, Lu, Qiong, Li, Zhihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344144/ https://www.ncbi.nlm.nih.gov/pubmed/32714929 http://dx.doi.org/10.3389/fcell.2020.00534 |
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