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Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain

Lorcaserin is a preferential serotonin2C receptor (5-HT(2C)R) agonist effective to treat obesity that has also recently been proposed to treat addiction and epilepsy. Central dopamine (DA) mechanisms are likely involved in the lorcaserin mechanism of action, but other monoamines 5-HT and noradrenali...

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Detalles Bibliográficos
Autores principales: Di Giovanni, Giuseppe, Bharatiya, Rahul, Puginier, Emilie, Ramos, Marta, De Deurwaerdère, Salomé, Chagraoui, Abdeslam, De Deurwaerdère, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344148/
https://www.ncbi.nlm.nih.gov/pubmed/32714188
http://dx.doi.org/10.3389/fphar.2020.00962