Cargando…

Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain

Lorcaserin is a preferential serotonin2C receptor (5-HT(2C)R) agonist effective to treat obesity that has also recently been proposed to treat addiction and epilepsy. Central dopamine (DA) mechanisms are likely involved in the lorcaserin mechanism of action, but other monoamines 5-HT and noradrenali...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di Giovanni, Giuseppe, Bharatiya, Rahul, Puginier, Emilie, Ramos, Marta, De Deurwaerdère, Salomé, Chagraoui, Abdeslam, De Deurwaerdère, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344148/ https://www.ncbi.nlm.nih.gov/pubmed/32714188 http://dx.doi.org/10.3389/fphar.2020.00962

Ejemplares similares

Chronic Administration of Fipronil Heterogeneously Alters the Neurochemistry of Monoaminergic Systems in the Rat Brain
por: Bharatiya, Rahul, et al.
Publicado: (2020)

Effect of the 5-HT(2C) Receptor Agonist WAY-163909 on Serotonin and Dopamine Metabolism across the Rat Brain: A Quantitative and Qualitative Neurochemical Study
por: Whitestone, Sara, et al.
Publicado: (2019)

Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases
por: De Deurwaerdère, Philippe, et al.
Publicado: (2021)

Editorial: Contemporary Perspective on 5-HT(2C) Receptor Function and Its Pharmacological Targeting
por: De Deurwaerdère, Philippe, et al.
Publicado: (2020)

Noradrenaline and Parkinson's Disease
por: Delaville, Claire, et al.
Publicado: (2011)

Cannabinoid 1/2 Receptor Activation Induces Strain-Dependent Behavioral and Neurochemical Changes in Genetic Absence Epilepsy Rats From Strasbourg and Non-epileptic Control Rats
por: De Deurwaerdère, Philippe, et al.
Publicado: (2022)

Neurobiological and Pharmacological Perspectives of D3 Receptors in Parkinson’s Disease
por: Chagraoui, Abdeslam, et al.
Publicado: (2022)

Serotonin in Animal Cognition and Behavior
por: Bacqué-Cazenave, Julien, et al.
Publicado: (2020)

Editorial: New GPCR targets and modulators to treat CNS disorders
por: De Deurwaerdère, Philippe, et al.
Publicado: (2022)

Serotonin in Health and Disease
por: De Deurwaerdère, Philippe, et al.
Publicado: (2020)

Pathophysiology of the Serotonin System in the Nervous System and Beyond
por: De Deurwaerdère, Philippe, et al.
Publicado: (2022)

LPM580098, a Novel Triple Reuptake Inhibitor of Serotonin, Noradrenaline, and Dopamine, Attenuates Neuropathic Pain
por: Li, Nannan, et al.
Publicado: (2019)

L-DOPA in Parkinson’s Disease: Looking at the “False” Neurotransmitters and Their Meaning
por: Chagraoui, Abdeslam, et al.
Publicado: (2019)

Lead-Induced Atypical Parkinsonism in Rats: Behavioral, Electrophysiological, and Neurochemical Evidence for a Role of Noradrenaline Depletion
por: Sabbar, Mariam, et al.
Publicado: (2018)

Editorial: Non-Dopaminergic Systems in Parkinson’s Disease
por: Miguelez, Cristina, et al.
Publicado: (2020)

A Subset of Purposeless Oral Movements Triggered by Dopaminergic Agonists Is Modulated by 5-HT(2C) Receptors in Rats: Implication of the Subthalamic Nucleus
por: Lagière, Mélanie, et al.
Publicado: (2020)

Editorial: Insights on neuroinflammatory response by microglia-targeted pharmacology
por: Raber, Jacob, et al.
Publicado: (2023)

Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats
por: Khsime, Inès, et al.
Publicado: (2023)

Serotonin2C Receptors and the Motor Control of Oral Activity
por: Lagière, Mélanie, et al.
Publicado: (2013)

The Noradrenergic System in Parkinson’s Disease
por: Paredes-Rodriguez, Elena, et al.
Publicado: (2020)

Pimavanserin and Lorcaserin Attenuate Measures of Binge Eating in Male Sprague-Dawley Rats
por: Price, Amanda E., et al.
Publicado: (2018)

Dissociable effects of noradrenaline, dopamine, and serotonin uptake blockade on stop task performance in rats
por: Bari, Andrea, et al.
Publicado: (2009)

Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets
por: Jing, Muhan, et al.
Publicado: (2021)

Acute and Chronic Nicotine Exposures Differentially Affect Central Serotonin 2A Receptor Function: Focus on the Lateral Habenula
por: Bombardi, Cristiano, et al.
Publicado: (2020)

Lorcaserin for weight management
por: Taylor, James R, et al.
Publicado: (2013)

Serotonin and dopamine receptors in motivational and cognitive disturbances of schizophrenia
por: Sumiyoshi, Tomiki, et al.
Publicado: (2014)

Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia
por: Navailles, Sylvia, et al.
Publicado: (2012)

Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia
por: Welsch, Patrick, et al.
Publicado: (2018)

Serotonin, Dopamine and Noradrenaline Adjust Actions of Myelinated Afferents via Modulation of Presynaptic Inhibition in the Mouse Spinal Cord
por: García-Ramírez, David L., et al.
Publicado: (2014)

Monoamine content during the reproductive cycle of Perna perna depends on site of origin on the Atlantic Coast of Morocco
por: Klouche, Mounia S., et al.
Publicado: (2015)

Distinct Roles of Dopamine and Noradrenaline in Incidental Memory
por: Hauser, Tobias U., et al.
Publicado: (2019)

Dopamine and Noradrenaline in the Brain; Overlapping or Dissociate Functions?
por: Ranjbar-Slamloo, Yadollah, et al.
Publicado: (2020)

Serotonin syndrome triggered by postoperative administration of serotonin noradrenaline reuptake inhibitor (SNRI)
por: Takata, Junko, et al.
Publicado: (2019)

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum
por: Porras, Gregory, et al.
Publicado: (2014)

Manganese-Induced Atypical Parkinsonism Is Associated with Altered Basal Ganglia Activity and Changes in Tissue Levels of Monoamines in the Rat
por: Bouabid, Safa, et al.
Publicado: (2014)

Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis
por: Andreou, Dimitrios, et al.
Publicado: (2014)

Lorcaserin: A novel antiobesity drug
por: Brashier, Dick B. S., et al.
Publicado: (2014)

Role of Glycogenolysis in Memory and Learning: Regulation by Noradrenaline, Serotonin and ATP
por: Gibbs, Marie E.
Publicado: (2016)

Serotonin and Noradrenaline Reuptake Inhibitors Improve Micturition Control in Mice
por: Redaelli, Marco, et al.
Publicado: (2015)

A dopamine and noradrenaline reuptake inhibitor (bupropion) does not alter exercise performance of bank voles
por: Jaromin, Ewa, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_6e2b9uhvg2io3sipiodf89hr4b