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MicroRNA-221 Modulates Airway Remodeling via the PI3K/AKT Pathway in OVA-Induced Chronic Murine Asthma

BACKGROUND: Airway remodeling is one of the most important pathological features of chronic asthma. This study aimed to determine whether microRNA-221 (hereafter, miR-221) can affect airway remodeling in a mouse model of ovalbumin (OVA)-induced chronic asthma. METHODS: Adeno-associated viruses (AAVs...

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Detalles Bibliográficos
Autores principales: Pan, Jing, Yang, Qianyuan, Zhou, Yao, Deng, Huan, Zhu, Yifan, Zhao, Deyu, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344209/
https://www.ncbi.nlm.nih.gov/pubmed/32714925
http://dx.doi.org/10.3389/fcell.2020.00495