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Overview: Systemic Inflammatory Response Derived From Lung Injury Caused by SARS-CoV-2 Infection Explains Severe Outcomes in COVID-19

Most SARS-CoV2 infections will not develop into severe COVID-19. However, in some patients, lung infection leads to the activation of alveolar macrophages and lung epithelial cells that will release proinflammatory cytokines. IL-6, TNF, and IL-1β increase expression of cell adhesion molecules (CAMs)...

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Detalles Bibliográficos
Autores principales: Polidoro, Rafael B., Hagan, Robert S., de Santis Santiago, Roberta, Schmidt, Nathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344249/
https://www.ncbi.nlm.nih.gov/pubmed/32714336
http://dx.doi.org/10.3389/fimmu.2020.01626