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KDM5C Represses FASN-Mediated Lipid Metabolism to Exert Tumor Suppressor Activity in Intrahepatic Cholangiocarcinoma

Background: KDM5C is a histone H3K4-specific demethylase, which has multiple biological functions during development and disease. However, the role of KDM5C in intrahepatic cholangiocarcinoma (ICC) remains unknown. Methods: Expression levels of KDM5C in ICC patients were determined by qRT-PCR, weste...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhou, Bing-hai, Xiao, Min, Li, Hui, Guo, Lei, Wang, Meng-xi, Yu, Shan-he, Ye, Qing-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344276/
https://www.ncbi.nlm.nih.gov/pubmed/32714863
http://dx.doi.org/10.3389/fonc.2020.01025