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Targeting NK Cell Checkpoint Receptors or Molecules for Cancer Immunotherapy

Checkpoint blockade therapy, for example using antibodies against CTLA-4 and PD-1/PD-L1, relieves T cells from the suppression by inhibitory checkpoints in the tumor microenvironment; thereby achieving good outcomes in the treatment of different cancer types. Like T cells, natural killer (NK) cell i...

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Detalles Bibliográficos
Autores principales: Zhang, Cai, Liu, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344328/
https://www.ncbi.nlm.nih.gov/pubmed/32714324
http://dx.doi.org/10.3389/fimmu.2020.01295