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Targeting NK Cell Checkpoint Receptors or Molecules for Cancer Immunotherapy
Checkpoint blockade therapy, for example using antibodies against CTLA-4 and PD-1/PD-L1, relieves T cells from the suppression by inhibitory checkpoints in the tumor microenvironment; thereby achieving good outcomes in the treatment of different cancer types. Like T cells, natural killer (NK) cell i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344328/ https://www.ncbi.nlm.nih.gov/pubmed/32714324 http://dx.doi.org/10.3389/fimmu.2020.01295 |