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Clopidogrel, an ADP-P2Y12 Receptor Antagonist, Can Prevent Severe Postoperative Pain: A Retrospective Chart Review

The purinergic P2Y12 receptor regulates microglial activation, resulting in persistence and aggravation of pain in neuropathic and nociceptive pain models. We conducted a retrospective chart review to explore the analgesic potency of the P2Y12 receptor-specific antagonist, clopidogrel, for clinical...

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Detalles Bibliográficos
Autores principales: Tsuchida, Rikuhei, Sumitani, Masahiko, Abe, Hiroaki, Ando, Masae, Saita, Kosuke, Hattori, Kohshi, Mietani, Kazuhito, Inoue, Reo, Uchida, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344612/
https://www.ncbi.nlm.nih.gov/pubmed/32580286
http://dx.doi.org/10.3390/life10060092