Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal Malignancy

Matrix metalloproteinases (MMPs) are a family of enzymes involved at different stages of cancer progression and metastasis. We previously identified a novel class of bisphosphonic inhibitors, selective for MMPs crucial for bone remodeling, such as MMP-2. Due to the increasing relevance of specific M...

Descripción completa

Detalles Bibliográficos
Autores principales: Laghezza, Antonio, Piemontese, Luca, Brunetti, Leonardo, Caradonna, Alessia, Agamennone, Mariangela, Di Pizio, Antonella, Pochetti, Giorgio, Montanari, Roberta, Capelli, Davide, Tauro, Marilena, Loiodice, Fulvio, Tortorella, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344628/
https://www.ncbi.nlm.nih.gov/pubmed/32492898
http://dx.doi.org/10.3390/ph13060113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344628/
https://www.ncbi.nlm.nih.gov/pubmed/32492898
http://dx.doi.org/10.3390/ph13060113

Ejemplares similares