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Influence of Single Nucleotide Polymorphisms on Rifampin Pharmacokinetics in Tuberculosis Patients

Rifampin (RF) is metabolized in the liver into an active metabolite 25-desacetylrifampin and excreted almost equally via biliary and renal routes. Various influx and efflux transporters influence RF disposition during hepatic uptake and biliary excretion. Evidence has also shown that Vitamin D defic...

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Detalles Bibliográficos
Autores principales: Thomas, Levin, Sekhar Miraj, Sonal, Surulivelrajan, Mallayasamy, Varma, Muralidhar, Sanju, Chidananda S. V., Rao, Mahadev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344705/
https://www.ncbi.nlm.nih.gov/pubmed/32521634
http://dx.doi.org/10.3390/antibiotics9060307