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Structural Modifications of 3-Triazeneindoles and Their Increased Activity Against Mycobacterium tuberculosis
We synthesized 100 novel indole-based compounds with polyaza-functionalities, including 3-triazeneindoles, and tested their activity in vitro against laboratory M. tuberculosis H37Rv and clinical izoniazid-resistant CN-40 isolates, using gross and fine titration approaches. Here we present a few 3-t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344711/ https://www.ncbi.nlm.nih.gov/pubmed/32599854 http://dx.doi.org/10.3390/antibiotics9060356 |