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Molecular Interaction Characterization Strategies for the Development of New Biotherapeutic Antibody Modalities

The characterization of target binding interactions is critical at each stage of antibody therapeutic development. During early development, it is important to design fit-for-purpose in vitro molecular interaction characterization (MIC) assays that accurately determine the binding kinetics and the a...

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Detalles Bibliográficos
Autores principales: Wang, Xiangdan, Phan, Minh Michael, Li, Ji, Gill, Herman, Williams, Simon, Gupta, Nidhi, Quarmby, Valerie, Yang, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344756/
https://www.ncbi.nlm.nih.gov/pubmed/32218192
http://dx.doi.org/10.3390/antib9020007