A Novel Derivative of Thioridazine Shows Low Toxicity and Efficient Activity against Gram-Positive Pathogens

Thioridazine hydrochloride (HCl) has been suggested as a promising antimicrobial helper compound for the treatment of infections with antimicrobial-resistant bacteria. Unfortunately, the therapeutic concentration of thioridazine HCl is generally higher than what can be tolerated clinically, in part...

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Detalles Bibliográficos
Autores principales: Jørgensen, Nadia S., Saaby, Lasse, Andersson, Anne M., Kromann, Sofie, Sheikhsamani, Ehsan, Permin, Anders, Ronco, Troels, Svenningsen, Søren W., Christensen, Jørn B., Olsen, Rikke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344759/
https://www.ncbi.nlm.nih.gov/pubmed/32549350
http://dx.doi.org/10.3390/antibiotics9060327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344759/
https://www.ncbi.nlm.nih.gov/pubmed/32549350
http://dx.doi.org/10.3390/antibiotics9060327

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