Excess Ascorbate is a Chemical Stress Agent against Proteins and Cells

Excess ascorbate (as expected in intravenous treatment proposed for COVID-19 management, for example) oxidizes and/or degrades hemoglobin and albumin, as evidenced by UV-vis spectroscopy, gel electrophoresis, and mass spectrometry. It also degrades hemoglobin in intact blood or in isolated erythrocy...

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Detalles Bibliográficos
Autores principales: Lehene, Maria, Fischer-Fodor, Eva, Scurtu, Florina, Hădade, Niculina D., Gal, Emese, Mot, Augustin C., Matei, Alina, Silaghi-Dumitrescu, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344896/
https://www.ncbi.nlm.nih.gov/pubmed/32471171
http://dx.doi.org/10.3390/ph13060107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344896/
https://www.ncbi.nlm.nih.gov/pubmed/32471171
http://dx.doi.org/10.3390/ph13060107

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