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17β-Estradiol Promotes Proinflammatory and Procoagulatory Phenotype of Innate Immune Cells in the Presence of Antiphospholipid Antibodies

Antiphospholipid syndrome (APS) is the most common cause of acquired thrombophilia and recurrent spontaneous miscarriages associated with extended persistence of antiphospholipid antibodies (aPL). How circulating aPL and high-17β-estradiol (E2) environment contribute to the pregnancy complications i...

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Detalles Bibliográficos
Autores principales: Manukyan, Gayane, Martirosyan, Anush, Slavik, Ludek, Ulehlova, Jana, Dihel, Martin, Papajik, Tomas, Kriegova, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345022/
https://www.ncbi.nlm.nih.gov/pubmed/32549383
http://dx.doi.org/10.3390/biomedicines8060162