Cargando…
17β-Estradiol Promotes Proinflammatory and Procoagulatory Phenotype of Innate Immune Cells in the Presence of Antiphospholipid Antibodies
Antiphospholipid syndrome (APS) is the most common cause of acquired thrombophilia and recurrent spontaneous miscarriages associated with extended persistence of antiphospholipid antibodies (aPL). How circulating aPL and high-17β-estradiol (E2) environment contribute to the pregnancy complications i...
Autores principales: | Manukyan, Gayane, Martirosyan, Anush, Slavik, Ludek, Ulehlova, Jana, Dihel, Martin, Papajik, Tomas, Kriegova, Eva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345022/ https://www.ncbi.nlm.nih.gov/pubmed/32549383 http://dx.doi.org/10.3390/biomedicines8060162 |
Ejemplares similares
-
Anti-domain 1 β2 glycoprotein antibodies increase expression of tissue factor on monocytes and activate NK Cells and CD8+ cells in vitro
por: Manukyan, Gayane, et al.
Publicado: (2020) -
Current Promising Biomarkers and Methods in the Diagnostics of Antiphospholipid Syndrome: A Review
por: Bradacova, Pavla, et al.
Publicado: (2021) -
Determination of Thrombogenicity Levels of Various Antiphospholipid Antibodies by a Modified Thrombin Generation Assay in Patients with Suspected Antiphospholipid Syndrome
por: Bradáčová, Pavla, et al.
Publicado: (2022) -
Differential Regulation of Proinflammatory Mediators following LPS- and ATP-Induced Activation of Monocytes from Patients with Antiphospholipid Syndrome
por: Martirosyan, Anush, et al.
Publicado: (2015) -
Environmental Triggers of Autoreactive Responses: Induction of Antiphospholipid Antibody Formation
por: Martirosyan, Anush, et al.
Publicado: (2019)