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Sirolimus-Eluting Electrospun-Produced Matrices as Coatings for Vascular Stents: Dependence of Drug Release on Matrix Structure and Composition of the External Environment

Although a number of drug-eluting coatings for vascular stents (VSs) have been developed and are in commercial use, more efficient stent coatings and drug delivery systems are needed. Sirolimus (SRL) is a clinically important drug with antiproliferative and immunosuppressive activities that is widel...

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Detalles Bibliográficos
Autores principales: Nazarkina, Zhanna K., Chelobanov, Boris P., Chernonosova, Vera S., Romanova, Irina V., Karpenko, Andrey A., Laktionov, Pavel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345069/
https://www.ncbi.nlm.nih.gov/pubmed/32545664
http://dx.doi.org/10.3390/ma13122692