Cargando…

From Orai to E-Cadherin: Subversion of Calcium Trafficking in Cancer to Drive Proliferation, Anoikis-Resistance, and Metastasis

The common currency of epithelial differentiation and homeostasis is calcium, stored primarily in the endoplasmic reticulum, rationed according to need, and replenished from the extracellular milieu via store-operated calcium entry (SOCE). This currency is disbursed by the IP3 receptor in response t...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Aarushi, Elble, Randolph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345168/
https://www.ncbi.nlm.nih.gov/pubmed/32575848
http://dx.doi.org/10.3390/biomedicines8060169