Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus

Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant mutants of the thermophilic b...

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Detalles Bibliográficos
Autores principales: Killeavy, Erin E., Jogl, Gerwald, Gregory, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345174/
https://www.ncbi.nlm.nih.gov/pubmed/32526926
http://dx.doi.org/10.3390/antibiotics9060313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345174/
https://www.ncbi.nlm.nih.gov/pubmed/32526926
http://dx.doi.org/10.3390/antibiotics9060313

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