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Tiamulin-Resistant Mutants of the Thermophilic Bacterium Thermus thermophilus
Tiamulin is a semisynthetic pleuromutilin antibiotic that binds to the 50S ribosomal subunit A site and whose (((2-diethylamino)ethyl)thio)-acetic acid tail extends into the P site to interfere with peptide bond formation. We have isolated spontaneous tiamulin-resistant mutants of the thermophilic b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345174/ https://www.ncbi.nlm.nih.gov/pubmed/32526926 http://dx.doi.org/10.3390/antibiotics9060313 |