Paclitaxel, Imatinib and 5-Fluorouracil Increase the Unbound Fraction of Flucloxacillin In Vitro

Flucloxacillin (FLU), an isoxazolyl penicillin, is widely used for the treatment of different bacterial infections in intensive care units (ICU). Being highly bound to plasma proteins, FLU is prone to drug-drug interactions (DDI) when administered concurrently with other drugs. As FLU is binding to...

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Detalles Bibliográficos
Autores principales: Stolte, Maximilian, Ali, Weaam, Jänis, Janne, Gessner, Andre’, El-Najjar, Nahed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345279/
https://www.ncbi.nlm.nih.gov/pubmed/32521723
http://dx.doi.org/10.3390/antibiotics9060309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345279/
https://www.ncbi.nlm.nih.gov/pubmed/32521723
http://dx.doi.org/10.3390/antibiotics9060309

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