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Transcriptome-Wide Analysis of CXCR5 Deficient Retinal Pigment Epithelial (RPE) Cells Reveals Molecular Signatures of RPE Homeostasis

Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in the elderly population. In our previous studies, we found that deficiency of CXCR5 causes AMD-like pathological phenotypes in mice, characterized by abnormalities and dysfunction of the retinal pigment epith...

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Detalles Bibliográficos
Autores principales: Saddala, Madhu Sudhana, Lennikov, Anton, Mukwaya, Anthony, Huang, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345337/
https://www.ncbi.nlm.nih.gov/pubmed/32492870
http://dx.doi.org/10.3390/biomedicines8060147