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Chloroquine kills hair cells in zebrafish lateral line and murine cochlear cultures: Implications for ototoxicity

Hearing and balance deficits have been reported during and following treatment with the antimalarial drug chloroquine. However, experimental work examining the direct actions of chloroquine on mechanoreceptive hair cells in common experimental models is lacking. This study examines the effects of ch...

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Detalles Bibliográficos
Autores principales: Davis, Samantha N., Wu, Patricia, Camci, Esra D., Simon, Julian A., Rubel, Edwin W., Raible, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345387/
https://www.ncbi.nlm.nih.gov/pubmed/32768772
http://dx.doi.org/10.1016/j.heares.2020.108019