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Potential Anti-Tumor Drug: Co-Crystal 5-Fluorouracil-nicotinamide

[Image: see text] 5-Fluorouracil-nicotinamide (5-FU-NCM), a co-crystal with a 2D layer structure formed by hydrogen bonds, was synthesized by solvent evaporation and liquid phase-assisted grinding at room temperature. Compared to 5-FU alone, the results of solubility, oil–water partition coefficient...

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Detalles Bibliográficos
Autores principales: Zhang, Zhuyan, Yu, Nan, Xue, Chang, Gao, Shan, Deng, Zhaopeng, Li, Min, Liu, Cong, Castellot, John, Han, Siying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345411/
https://www.ncbi.nlm.nih.gov/pubmed/32656396
http://dx.doi.org/10.1021/acsomega.9b03574