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Potential Anti-Tumor Drug: Co-Crystal 5-Fluorouracil-nicotinamide
[Image: see text] 5-Fluorouracil-nicotinamide (5-FU-NCM), a co-crystal with a 2D layer structure formed by hydrogen bonds, was synthesized by solvent evaporation and liquid phase-assisted grinding at room temperature. Compared to 5-FU alone, the results of solubility, oil–water partition coefficient...
Autores principales: | Zhang, Zhuyan, Yu, Nan, Xue, Chang, Gao, Shan, Deng, Zhaopeng, Li, Min, Liu, Cong, Castellot, John, Han, Siying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345411/ https://www.ncbi.nlm.nih.gov/pubmed/32656396 http://dx.doi.org/10.1021/acsomega.9b03574 |
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