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Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective

The tumor microenvironment (TME) comprises complex interactions of multiple cell types that determines cell behavior and metabolism such as nutrient competition and immune suppression. We discuss the various types of heterogeneity that exist in solid tumors, and the complications this invokes for st...

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Detalles Bibliográficos
Autores principales: Fan, Teresa W. -M., Higashi, Richard M., Chernayavskaya, Yelena, Lane, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345423/
https://www.ncbi.nlm.nih.gov/pubmed/32549391
http://dx.doi.org/10.3390/metabo10060249