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Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages

(1) Background: Neosaxitoxin (NeoSTX) has been used as a local anesthetic, but its anti-inflammatory effects have not been well defined. In the present study, we investigate the effects of NeoSTX on lipopolysaccharide (LPS)-activated macrophages. (2) Methods: Raw 264.7 and equine PBMC cells were inc...

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Detalles Bibliográficos
Autores principales: Montero, M. Cecilia, del Campo, Miguel, Bono, M., Simon, M. Valeska, Guerrero, Julia, Lagos, Néstor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345530/
https://www.ncbi.nlm.nih.gov/pubmed/32471037
http://dx.doi.org/10.3390/md18060283