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Overexpression of Kif1A in the Developing Drosophila Heart Causes Valvar and Contractility Defects: Implications for Human Congenital Heart Disease

Left-sided congenital heart defects (CHDs) are among the most common forms of congenital heart disease, but a disease-causing gene has only been identified in a minority of cases. Here, we identified a candidate gene for CHDs, KIF1A, that was associated with a chromosomal balanced translocation t(2;...

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Detalles Bibliográficos
Autores principales: Akasaka, Takeshi, Ocorr, Karen, Lin, Lizhu, Vogler, Georg, Bodmer, Rolf, Grossfeld, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345553/
https://www.ncbi.nlm.nih.gov/pubmed/32498427
http://dx.doi.org/10.3390/jcdd7020022