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Characterization of Synthetic Tf2 as a Na(V)1.3 Selective Pharmacological Probe

Na(V)1.3 is a subtype of the voltage-gated sodium channel family. It has been implicated in the pathogenesis of neuropathic pain, although the contribution of this channel to neuronal excitability is not well understood. Tf2, a β-scorpion toxin previously identified from the venom of Tityus fasciola...

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Detalles Bibliográficos
Autores principales: Israel, Mathilde R., Dash, Thomas S., Bothe, Stefanie N., Robinson, Samuel D., Deuis, Jennifer R., Craik, David J., Lampert, Angelika, Vetter, Irina, Durek, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345637/
https://www.ncbi.nlm.nih.gov/pubmed/32545167
http://dx.doi.org/10.3390/biomedicines8060155