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Understanding the Mechanism of Recognition of Gab2 by the N-SH2 Domain of SHP2
Gab2 is a scaffold protein with a crucial role in colocalizing signaling proteins and it is involved in the regulation of several important molecular pathways. SHP2 is a protein phosphatase that binds, through its two SH2 domains, specific consensus sequences presenting a phosphorylated tyrosine loc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345789/ https://www.ncbi.nlm.nih.gov/pubmed/32545165 http://dx.doi.org/10.3390/life10060085 |