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Metabolic Endotoxemia, Feeding Studies and the Use of the Limulus Amebocyte (LAL) Assay; Is It Fit for Purpose?

The Limulus amebocyte assay (LAL) is increasingly used to quantify metabolic endotoxemia (ME), particularly in feeding studies. However, the assay was not intended to assess plasma at levels typically seen in ME. We aimed to optimize and validate the LAL assay under a range of pre-treatment conditio...

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Detalles Bibliográficos
Autores principales: Pearce, Karma, Estanislao, Dianne, Fareed, Sinan, Tremellen, Kelton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345849/
https://www.ncbi.nlm.nih.gov/pubmed/32599766
http://dx.doi.org/10.3390/diagnostics10060428