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Structural Elucidation of Antibiotic TKR2999, an Antifungal Lipodepsipeptide Isolated from the Fungus Foliophoma fallens

An antifungal lipodepsipeptide was obtained from cultures of the fungus Foliophoma fallens CF-236885. Its structure, elucidated by HRMS and NMR spectroscopy, contained Gly, Thr, Asn, β-Ala, Orn, Ala, two Ser residues, and 3-hydroxy-4-methylhexadecanoic acid. The absolute configuration of its amino a...

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Detalles Bibliográficos
Autores principales: Crespo, Gloria, Pérez-Victoria, Ignacio, Ortiz-López, Francisco Javier, González-Menéndez, Víctor, de la Cruz, Mercedes, Cautain, Bastien, Sánchez, Pilar, Vicente, Francisca, Genilloud, Olga, Reyes, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345921/
https://www.ncbi.nlm.nih.gov/pubmed/32466351
http://dx.doi.org/10.3390/antibiotics9060278