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Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α

Microglial cells are the first line immune cells that initiate inflammatory responses following cerebral ischemia/reperfusion(I/R) injury. Microglial cells are also associated with a novel subtype of pro-inflammatory programmed cell death known as pyroptosis. Research has been directed at developing...

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Detalles Bibliográficos
Autores principales: Huang, Yan, Tan, Fengbo, Zhuo, Yi, Liu, Jianyang, He, Jialin, Duan, Da, Lu, Ming, Hu, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346036/
https://www.ncbi.nlm.nih.gov/pubmed/32507769
http://dx.doi.org/10.18632/aging.103307