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Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α
Microglial cells are the first line immune cells that initiate inflammatory responses following cerebral ischemia/reperfusion(I/R) injury. Microglial cells are also associated with a novel subtype of pro-inflammatory programmed cell death known as pyroptosis. Research has been directed at developing...
Autores principales: | Huang, Yan, Tan, Fengbo, Zhuo, Yi, Liu, Jianyang, He, Jialin, Duan, Da, Lu, Ming, Hu, Zhiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346036/ https://www.ncbi.nlm.nih.gov/pubmed/32507769 http://dx.doi.org/10.18632/aging.103307 |
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