Lactate dehydrogenase expression modulates longevity and neurodegeneration in Drosophila melanogaster

Lactate dehydrogenase (LDH) catalyzes the conversion of glycolysis-derived pyruvate to lactate. Lactate has been shown to play key roles in brain energetics and memory formation. However, lactate levels are elevated in aging and Alzheimer’s disease patients, and it is not clear whether lactate plays...

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Detalles Bibliográficos
Autores principales: Long, Dani M., Frame, Ariel K., Reardon, Patrick N., Cumming, Robert C., Hendrix, David A., Kretzschmar, Doris, Giebultowicz, Jadwiga M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346061/
https://www.ncbi.nlm.nih.gov/pubmed/32484787
http://dx.doi.org/10.18632/aging.103373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346061/
https://www.ncbi.nlm.nih.gov/pubmed/32484787
http://dx.doi.org/10.18632/aging.103373

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