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Anti-Migratory Effects of 4′-Geranyloxyferulic Acid on LPS-Stimulated U937 and HCT116 Cells via MMP-9 Down-Regulation: Involvement of ROS/ERK Signaling Pathway

Matrix metalloproteinases (MMPs) play a crucial role in tumor angiogenesis, and metastasis. 4′-geranyloxyferulic acid (GOFA) has anti-tumor and anti-inflammatory proprieties. Herein, we aimed to determine whether this compound affects cell survival, invasion, and migration through reactive oxygen sp...

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Detalles Bibliográficos
Autores principales: Franceschelli, Sara, Gatta, Daniela Maria Pia, Ferrone, Alessio, Mezza, Giulia, Speranza, Lorenza, Pesce, Mirko, Grilli, Alfredo, Gallorini, Marialucia, Giacomo, Viviana di, Ghinassi, Barbara, Fiorito, Serena, Genovese, Salvatore, Ricciotti, Emanuela, Felaco, Mario, Patruno, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346147/
https://www.ncbi.nlm.nih.gov/pubmed/32492880
http://dx.doi.org/10.3390/antiox9060470