Impact of the APE1 Redox Function Inhibitor E3330 in Non-Small Cell Lung Cancer Cells Exposed to Cisplatin: Increased Cytotoxicity and Impairment of Cell Migration and Invasion

Elevated expression levels of the apurinic/apyrimidinic endonuclease 1 (APE1) have been correlated with the more aggressive phenotypes and poor prognosis of non-small cell lung cancer (NSCLC). This study aimed to assess the impact of the inhibition of the redox function of APE1 with E3330 either alo...

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Detalles Bibliográficos
Autores principales: Manguinhas, Rita, Fernandes, Ana S., Costa, João G., Saraiva, Nuno, Camões, Sérgio P., Gil, Nuno, Rosell, Rafael, Castro, Matilde, Miranda, Joana P., Oliveira, Nuno G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346157/
https://www.ncbi.nlm.nih.gov/pubmed/32599967
http://dx.doi.org/10.3390/antiox9060550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346157/
https://www.ncbi.nlm.nih.gov/pubmed/32599967
http://dx.doi.org/10.3390/antiox9060550

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